U ka ima joang kapele ka metformin? .
Lingaka tsa basali li sebelisa metformin e le karolo ea kalafo ho ima; re u joetsa joang:
Metformin ho ima
Basali ba nang le insulin ho hanyetsa e kanna ea ba le tse fapaneng mathata a basali , ho kenyelletsa le bothata ba ho ima. Ka hona, litsebi tsa mafu a basali li thuisa ka metformin ho thusa basali ho laola insulin ho hanyetsa 'me kahoo ba boloke nako e lekaneng ea ho ilela khoeli le ho fumana bokhachane.
Metformin ha e joalo kalafo ea ho hloka thari , empa eona e thusa ho laola ho ilela khoeli ea basali ba anngoeng ke insulin ho hanyetsa 'me ka tsela eo fihlella bokhachane habonolo . Hape, haeba mosali a laola ho itoanela ha insulin, a ke ke a ima feela empa o tla fokotsa menyetla ea ho lahleheloa ke lesea likhoeling tse latelang tsa bokhachane.
Ha mosali a khona ho leka-lekanya boemo ba hae ba li-hormone, ho bonts'a Ngaka ea ka hare José Víctor Manuel Rincón Ponce, oa Setsi sa Ts'ireletso ea Sechaba sa Mexico, methati ea hae ea ho ilela khoeli le eona e lula e le teng, ka hona ho tla ba bonolo ho hlahisa tikoloho e ntle bakeng sa 'mele oa hae ho Ho ba le boimana ba nako eohle.
Ho ima o tšoeroe ke polycystic ovary syndrome
Polycystic ovary syndrome, lefu le khetholloang ka linako tse sa tloaelehang, phetoho ea lihormone, le ponahalo ea li-cysts tse ngata mae a bomme, e ama hoo e ka bang 8% ea basali. Se bakang bolwetse bona e ntse e le pelaelo, mme tlhahlobo le kalafo ho buisanoe haholo ka tsona.
Se tsebahalang ke hore lena ke le leng la mabaka a mantlha a ho hloka thari ho basali, moo o ka eketsang mathata a ts'ebetsong, joalo ka botenya kapa ho hanela insulin.
Phuputso e entsoeng ke sehlopha sa bafuputsi ba tsoang liunivesithing tse fapaneng tsa Amerika, molemong oa ho tiisa sephetho sa lithuto tse nyane ho Mokhoa o motle oa ho phekola ho hloka thari ho basali ba nang le polycystic ovarian syndrome , 'me e seng e phatlalalitsoe ho The New magazine England Journal of Medicine, e hlalosa hore moriana oa khale o ne o sebelisetsoa ho hlohlelletsa mahe ka lebaka la ketso ea ona holima hormone e susumetsang, clomiphene citrate, ke khetho e ntle ho basali ba nang le bothata bona ho ima , hape ke kalafo e bonolo ka ho fetisisa, e theko e tlaase, e bolokehileng le e sebetsang.
Ts'ebetsong ea morao-rao e ne e le metformin, moriana o sebelisetsoang ho alafa lefu la tsoekere la mofuta oa 2, leo ka ho ntlafatsa tsoekere le botenya le ratang ho emoloa. Phuputso e entsoe le basali ba 626 ba hlokang thari ka lebaka la lefu lena mme ba ba aba ka lihlopha tse tharo, sehlopha se le seng se fumane sethibela-mafu (metformin ea tokollo e atolositsoeng), se seng sa inducer ea ovulation (clomiphene citrate) mme sa boraro se fumane meriana e 'meli . Kalafo le ts'alo-morao li nkile libeke tse 30 ho fihlela ba fihletse bokhachane.
Qetellong ea thuto, basali ba neng ba amohetse clomiphene ba bontšitse sekhahla sa tsoalo makhetlo a mararo ho feta a sehlopha sa metformin; Ntle le moo, ea pele le eona e bile le palo e phahameng ea bokhachane bo bongata.
Bao ba nkileng motsoako oa litlhare ka bobeli ba bonts'itse sekhahla sa ho ruruha ho feta tse ling kaofela, empa tsoalo ha ea ka ea phethahala, leha e ne e ts'oana le bokhachane bo bongata le sehlopha se fumaneng inducer ea ovulation.
Liphuputso tse fetileng li ne li fane ka maikutlo a fapaneng le sena, empa sephetho ha sea ka sa hlahlojoa ha se hlaha, empa ka sekhahla sa ho ruruha, e seng takatso ea basali ba nang le bothata bona.
Litšupiso:
Sengoloa sa Watch Lintlha tse ling
- Barbieri RL, et al. (2017). Metformin bakeng sa kalafo ea polycystic ovary syndrome.
uptodate.com/contents/metformin-for-treatment-of-the-polycystic-ovary-syndrome - Ikemisetse ho etsa liqeto tse nepahetseng ho thusa ho thibela likoli. (2017).
cdc.gov/ncbddd/birthdefects/prevention.html - Feig DS, le al. (2011). Phekolo ea Metformin nakong ea bokhachane. ETSA:
doi.org/10.2337/dc11-1153 - Matlapa a Glucophage (metformin hydrochloride); Glucophage XR (metformin hydrochloride) matlapa a ntlafatso. (2017).
fihlella.fda.gov/drugsatfda_docs/label/2017/020357s037s039,021202s021s023lbl.pdf - Basebetsi ba Mayo Clinic. (2017). Gestational lefu la tsoekere.
mayoclinic.org/diseases-conditions/gestational-diabetes/basics/risk-factors/con-20014854
Tse ka Hare